Substance Induced Depressive Disorder

Substance Induced Depressive Disorder

  • A form of depression that is directly caused by using alcohol, drugs, or medications.
  • Unlike the temporary hangover or crash from alcohol or drug use the feelings and symptoms last for much longer.
  • Most important is that Depression did not exist prior to the use of alcohol, drugs or various medications.
  • There must be severe symptoms that are not in the period of intoxication or withdrawal (i.e. the symptoms last for a period of time).
  • Interestingly there are substances that can have the onset of depression during intoxication or during withdrawal.

Medications Commonly Known to Cause Depression

  • Steroids (prednisone)
  • L-dopa (Parkinsons disease)
  • Certain Antibiotics
  • Chemotherapeutic agents
  • Immunological suppressants
  • Dermatological agent (certain acne medicines)

Alcohol and Drugs that May Cause Depression

  • Alcohol
  • Cocaine (often referred to as the cocaine “crash”)
  • Anxiolytic (Xanax, klonopin)
  • Amphetamine
  • Hallucinogen
  • Inhalant (spray paint, nitrous)
  • Opioid (heroin)
  • Sedative
  • Hypnotic


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